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Can psilocybin help ease existential despair in patients with advanced cancer? CU researchers hope to find out.

Published Fri, 21 Feb 2025 10:29:04 GMT

A new study in Colorado is trying to answer definitively whether psychedelics help at least some patients dealing with distress over advanced cancer.Dr. Stacy Fischer, co-leader of cancer prevention and control at the University of Colorado Cancer Center, said several small studies have found that psychedelic drugs may help patients who are experiencing demoralization or despair because of their impending mortality. The study CU is part of will have a larger and more diverse group of people, which hopefully will produce more conclusive evidence of whether there’s a benefit, she said.“There’s so much science that needs to be done in this space,” Fischer said.Psilocybin, the active ingredient in magic mushrooms, is still a Schedule 1 drug, meaning the U.S. Drug Enforcement Administration determined it has high potential for misuse and no accepted medical use.But the U.S. Food and Drug Administration also released guidance earlier this year for trials involving ...

Kurtenbach: The 49ers’ biggest weakness is now impossible to miss

Published Fri, 21 Feb 2025 10:29:04 GMT

SANTA CLARA — Conventional NFL roster-building says to build from the inside out. The closer you are to the ball at the line of scrimmage, it’s alleged, the more critical you are.Niners coach Kyle Shanahan doesn’t subscribe to that school of thought.And, sure enough, six games into the 49ers’ campaign, it’s undeniable that San Francisco has an issue on the interior of its offensive line.It’s the type of issue that might not change Monday night’s game with the Vikings, but it will almost certainly prove problematic when they play the NFC’s best down the line this season.Yes, it took six games to find a flaw in the 49ers’ winning machine, but now that it’s been identified, it won’t be easy to ignore. In fact, you might not see anything else.It was right there, in the middle of everything.How did we miss it?The Browns’ defense created a blueprint for how to beat the 49ers last Sunday. It, ironically, is to play a lot lik...

Warriors: Andre Iguodala says he’s retiring from NBA

Published Fri, 21 Feb 2025 10:29:04 GMT

Andre Iguodala took his time deciding, but ultimately chose to retire from the NBA this offseason after 19 seasons and four championships.Iguodala’s retirement news was published Friday morning by the New York Times and ESPN.All four of those NBA Finals wins came since joining the Warriors in 2013 and becoming a do-it-all sixth man who helped connect Golden State’s title teams over the next half-decade.Iguodala, 39, famously was named the 2015 NBA Finals MVP on the strength of his defensive work against Cavaliers star LeBron James as the Warriors won the six-game series to capture their first championship in four decades. He also moved into the starting lineup for the final three games of the series, all of which were wins against a Cleveland team reduced by injury.He was also a key player on the 2017 and 2018 title teams, though the Warriors relied less on him with Kevin Durant on the roster.His basketball intelligence paired with his slashing offensive style and physic...

Fremont tech and industrial park is bought by big real estate firm

Published Fri, 21 Feb 2025 10:29:04 GMT

FREMONT — A Fremont tech and industrial park has landed a big Texas real estate firm as a buyer in a deal that shows rising property values for the site despite a post-coronavirus economic landscape that can be hazardous.Hines Interests, acting through an affiliate, bought the two-building complex in a $40.4 million deal, according to documents filed on Oct. 11 with the Alameda County Recorder’s Office.The two buildings have addresses that include 48603 and 48633 Warm Springs Road in Fremont. The current tenants in the industrial park include an electronics manufacturer, energy firms and a maker of optical products.The vast Tesla electric vehicle factory is located a few miles away. The area is dotted with an array of tech and advanced manufacturing companies.Texas-based Hines is one of the nation’s largest and most successful development and investment firms whose transactions and projects are sometimes seen as bellwethers for the current state of the commercial r...

Jack White says new White Stripes lyrics book brought him to happy tears

Published Fri, 21 Feb 2025 10:29:04 GMT

Jack White usually has a guitar in his hands when the 12-time Grammy Award winner gets on a stage in Detroit.But on Wednesday night, Oct. 18, White was speaking — about words, and about the music of words.The Detroit native was back in town to discuss the new book, “The White Stripes Complete Lyrics 1997-2007,” published earlier in the month by his Third Man Books imprint, at Third Man Records Cass Corridor. He was questioned by Third Man co-owner Ben Blackwell and writer Hanif Abdurraqib, who both penned essays for the collection, while another essayist, Caroline Randall Williams, was one of three poets who read works before the discussion, which was part of the Great Lakes Independent Booksellers Association’s Heartland Fall Forum taking place this week in Detroit.‘The White Stripes Complete Lyrics 1997-2007’ was published earlier this month by Third Man Books (Courtesy Third Man Books) Noting that he “hadn’t thought through this book since we kind of roughly put it together,...

Beach hazards statement issued Friday due to threat of sneaker waves at the coast

Published Fri, 21 Feb 2025 10:29:04 GMT

(BCN) -- The National Weather Service issued a Beach Hazards Statement on Friday, saying that dangerous beach conditions along the Bay Area coast will linger as a northwest swell continues to send sneaker waves onto the region's shores.Friday's Beach Hazard Statement replaced the High Surf Advisory that was put up Thursday to account for lingering dangerous conditions at Bay Area beaches, weather service officials said.Sneaker waves -- large, unexpected waves that sweep across a beach without warning -- are expected through late Friday night, the agency added.Affected areas include San Francisco, the coastal North Bay including Point Reyes National Seashore, the San Francisco Peninsula coast, northern and southern Monterey Bay, and the Big Sur coast. October heat broke records in several Bay Area cities The weather service said that the northwest swell, while diminishing, remains energetic into Friday. Breaking waves of 10 to 15 feet are still possible throughout the day.Forecaste...

Highway 87 in San Jose closes for the weekend

Published Fri, 21 Feb 2025 10:29:04 GMT

(KRON) -- The southbound lanes of Highway 87 in San Jose will close for the weekend for  Caltrans’ repaving project. This closure will begin on Friday, Oct. 20 at 9 p.m. and is expected to reopen on Monday, Oct. 23 at 5 a.m.  October heat broke records in several Bay Area cities Here are the northbound detours.Take southbound SR-85 to northbound US-101 to northbound I-280Take northbound SR-85 to northbound SR-17 to southbound I-280Here are the southbound detoursTake southbound I-280 to southbound US-101 to northbound SR-85Take northbound I-280 to southbound SR-17 to southbound SR-85This closure will primarily impact southbound traffic from Blossom Hill Road to East Julian Street. The repaving project will not impact downtown San Jose. Residents who are traveling to the airport will not have an issue getting to their destination. 

Are Californians still taking over Texas? New Census data reveals where people are moving most

Published Fri, 21 Feb 2025 10:29:04 GMT

(NEXSTAR) – The California exodus continues, new Census data released Thursday shows. In 2022, more than 817,000 people left the Golden State for somewhere else in the U.S. About 475,000 people decided to move to California last year, meaning California suffered a net loss of around 342,000 to other U.S. states. As in years prior, Texas was the No. 1 target for people fleeing California. About 102,000 ex-Californians sought greener – or more likely, cheaper – pastures in Texas last year. That's a modest drop from 2021. Other popular destinations for Californians to move were Arizona (74,157 people), Florida (50,701), Washington (49,968), Nevada (48,836) and Oregon (36,429). Young and wealthy Californians leaving the region for other states, study says “We are losing younger folks, and I think we will see people continuing to migrate where housing costs are lower,” Manuel Pastor, a professor of sociology and American Studies & Ethnicity at the University of Southern California...

A history of South Africa vs England at the Rugby World Cup

Published Fri, 21 Feb 2025 10:29:04 GMT

PARIS (AP) — A brief history of Rugby World Cup matches between South Africa and England before they meet again on Saturday in the semifinals at Stade de France.1999 quarterfinal: South Africa 44, England 21 in ParisHenry Honiball was injured so backup Jannie de Beer played flyhalf for the defending champion Springboks and gave a kicking display that has passed into World Cup legend.A world record five drop goals — all in the second half — five penalties and two conversions added up to a sublime 12-from-12 shots at the posts by de Beer.A stop-start game turned into a kicking duel between de Beer and Paul Grayson until, at 22-18 in the second half, Grayson hit the crossbar and was replaced by Jonny Wilkinson. Wilkinson missed his first penalty shot but hit the second to trail 25-21.De Beer’s fourth drop then a fifth drop from 40 meters put South Africa beyond reach. Two more penalties sent de Beer past Percy Montgomery’s South Africa single game points record. One more go...

Israel says it doesn’t plan to control life in the Gaza Strip after its war with Hamas

Published Fri, 21 Feb 2025 10:29:04 GMT

Palestinian children displaced by the Israeli bombardment of the Gaza Strip walk in a UNDP-provided tent camp in Khan Younis on Thursday, Oct. 19, 2023. (AP Photo/Fatima Shbair)(AP/Fatima Shbair) Palestinian children displaced by the Israeli bombardment of the Gaza Strip walk in a UNDP-provided tent camp in Khan Younis on Thursday, Oct. 19, 2023. (AP Photo/Fatima Shbair)(AP/Fatima Shbair) KHAN YOUNIS, Gaza Strip (AP) — Israel said Friday it does not plan to take long-term control over the Gaza Strip after an expected ground offensive to root out Hamas militants that rule the territory. The Israeli military punished Gaza with airstrikes, and authorities inched closer to bringing aid to desperate families and hospit...